3,5-Dimethylpyrazole-1-carboximidamide hydrochloride
CAS: 40027-64-3
Ref. 3D-QBA02764
| 250mg | 337.00 € | ||
| 2500mg | 1,357.00 € |
Product Information
- 1H-pyrazole-1-carboximidamide, 3,5-dimethyl-, hydrochloride (1:1)
- 3,4,5-trimethyl-1H-pyrazole-1-carboximidamide hydrochloride
3,5-Dimethylpyrazole-1-carboximidamide hydrochloride is a test compound that can be used in enzyme preparations. It inhibits glyoxalase, which is an enzyme that catalyzes the reaction of glyoxal and lysine residues, preventing the formation of advanced glycation end products. 3,5-Dimethylpyrazole-1-carboximidamide hydrochloride has been shown to be a potent inhibitor of vesicular stomatitis virus (VSV) replication with high specificity for the aminoguanidine (AGA) site on VSV RNA polymerase. The mechanism for this inhibition is not fully understood; however, it is thought to involve the primary amines on 3,5-dimethylpyrazole-1-carboximidamide hydrochloride reacting with lysine residues on VSV RNA polymerase. This binding prevents amino acid activation and subsequent incorporation into the growing viral
Chemical properties
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