Product Information
3-(Hydroxymethyl)-2(1H)-quinolinone is a potent GABA antagonist with a low micromolar range of activity. It is used as a tool to evaluate the profile of GABA receptors and their kinetics, as well as to study the antagonistic activity at these receptors. 3-(Hydroxymethyl)-2(1H)-quinolinone has been shown to have antagonistic properties against glutamate and glycine receptors, although it does not bind to benzodiazepine or barbiturate binding sites. This drug has proapoptotic properties, which relates to its ability to induce neuronal cell death by apoptosis. 3-(Hydroxymethyl)-2(1H)-quinolinone also photolyzes in the presence of light and can be used for photodynamic therapy, which is an effective treatment for brain cancer.
Chemical properties
Technical inquiry about: 3D-QDA09745 3-(Hydroxymethyl)-2(1H)-quinolinone
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