2-Oxo-mirabegron N-carbamoylglucuronide

CAS: 1365244-66-1

Ref. 3D-QEC24466

Product Information

• Name: 2-Oxo-mirabegron N-carbamoylglucuronide
• Brand: Biosynth
• Description: 2-Oxo-mirabegron N-carbamoylglucuronide (2OMGC) is an impurity of mirabegron, a drug used to treat overactive bladder. 2OMGC is a metabolite of mirabegron that is created through the hydrolysis of the carbamate group on the nitrogen atom. This impurity can be detected in HPLC and GC/MS analyses and has been found in the urine of patients taking mirabegron. The detection limit for this impurity is 10 ng/mL. 2OMGC exhibits pharmacological activity similar to that of its parent compound, mirabegron, which is purported to have antispasmodic and anal sphincter relaxant properties.

Chemical properties

• Molecular weight: 614.60 g/mol
• Formula: C₂₈H₃₀N₄O₁₀S
• Purity: Min. 95%