Product Information
- 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, hydrochloride (1:1)
Crizotinib hydrochloride (CZH) is an anti-cancer drug that inhibits the enzyme tyrosine kinase. It is a porphyrin-based molecule that has a linker to crizotinib, a cytotoxic agent. CZH has been approved for the treatment of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in adults who have received at least one prior therapy. The effective dose of CZH is 400 mg twice per day. CZH has shown anticancer activity in vitro and in vivo and low toxicity.
Chemical properties
Technical inquiry about: 3D-QGC56069 Crizotinib hydrochloride
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