Crizotinib hydrochloride

Ref. 3D-QGC56069

Product Information

• Name: Crizotinib hydrochloride
• Brand: Biosynth
• Description: Crizotinib hydrochloride (CZH) is an anti-cancer drug that inhibits the enzyme tyrosine kinase. It is a porphyrin-based molecule that has a linker to crizotinib, a cytotoxic agent. CZH has been approved for the treatment of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in adults who have received at least one prior therapy. The effective dose of CZH is 400 mg twice per day. CZH has shown anticancer activity in vitro and in vivo and low toxicity.

Chemical properties

• Molecular weight: 486.8 g/mol
• Formula: C₂₁H₂₃Cl₃FN₅O
• Purity: Min. 95%