4-Fluoro-3-{5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl}aniline
CAS: 940242-26-2
Ref. 3D-QMB24226
1g | 728.00 € | ||
100mg | 183.00 € |
Product Information
4-Fluoro-3-[5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl]aniline (FTA) is a potent and selective inhibitor of the ion channels TRPV1 and TRPA1. It has been shown to inhibit the activity of these channels in both heterologous expression systems and native cells. FTA was originally developed as a tool for studying protein interactions with ion channels. It is also used as an anti-inflammatory agent in animal models of inflammatory pain.
TRPV1 is activated by noxious or potentially noxious stimuli such as heat, acidity (low pH), capsaicin (the active ingredient in chili peppers), and inflammation. This receptor is also activated by mechanical stimulation through its sensitivity to pressure and physical contact with irritant chemicals such as mustard oil and formalin. TRPA1 is activated by
Chemical properties
Technical inquiry about: 3D-QMB24226 4-Fluoro-3-{5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl}aniline
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.