Product Information
ASP4132 is a small molecule that has been shown to induce cell death in tumor cells through autophagy. It is orally active and can be used as a chemotherapeutic agent. ASP4132 activates the AMP-activated protein kinase, which inhibits the mTORC1 complex, leading to an increase in autophagy and apoptosis. The oral bioavailability of this drug is high and it has been shown to have limited toxicity. Clinical development for this drug is ongoing with toxicities such as anorexia, weight loss, dehydration, and elevated liver enzymes observed.
Chemical properties
Technical inquiry about: 3D-QQC29430 ASP4132
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