GSK2239633A

CAS: 1240516-71-5

Ref. 3D-QZB51671

Product Information

• Name: GSK2239633A
• Brand: Biosynth
• Description: GSK2239633A is a potent and selective inhibitor of IL-5 receptor alpha. It has been shown to inhibit the production of inflammatory cytokines in bronchial explants from asthma patients, as well as inhibiting chemotaxis and mucosal inflammation. GSK2239633A inhibits the synthesis of IL-5 by binding to the cytoplasmic domain of the IL-5 receptor alpha. This inhibition leads to reduced IL-5 production and subsequently a decrease in eosinophil recruitment into tissue. GSK2239633A also binds to other chemokine receptors, including CCR4 and CCR8, which may contribute to its anti-inflammatory effects.

Chemical properties

• Molecular weight: 549.06 g/mol
• Formula: C₂₄H₂₅ClN₄O₅S₂
• Purity: Min. 95%