Methylenebis-phosphonic acid tetramethyl ester
CAS: 16001-93-7
Ref. 3D-RAA00193
5g | 232.00 € | ||
10g | 407.00 € | ||
25g | 740.00 € | ||
50g | 1,275.00 € | ||
100g | 2,319.00 € |
Product Information
- Methylenediphosphonic acid tetramethyl ester
- Tetramethyl Methanediylbis(Phosphonate)
Methylenebisphosphonic acid is a phosphonic acid with an inhibitory effect on enzymes. It has been shown to have strong inhibitory properties against gram-negative bacteria and inhibits the growth of Mycobacterium tuberculosis. Methylenebisphosphonic acid also inhibits the production of cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), by inflammatory cells, which may contribute to its anti-inflammatory properties. Methylenebisphosphonic acid also blocks apoptotic cell death by inhibiting the activation of caspase 3, an enzyme that cleaves other proteins involved in apoptosis. Methylenebisphosphonic acid binds to Ca2+ response proteins and blocks their ability to regulate cellular processes. This prevents the release of cytochrome C from mitochondria, which initiates a cascade of reactions leading to cell death.
Chemical properties
Technical inquiry about: 3D-RAA00193 Methylenebis-phosphonic acid tetramethyl ester
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