Product Information
- 13a,14b,17bH-Lanost-7-en-3-one, 22,25-epoxy-23,24-dihydroxy- (8CI)
- Dehydroodoratol
Odoratone is a product research company that has developed a new series of potent, selective, and irreversible inhibitors of the protein tyrosine phosphatase 1B (PTP1B). Odoratone's lead inhibitor is DT-28-01. DT-28-01 inhibits PTP1B activity in vitro with an IC50 value of 8 nM. This inhibitor also exhibits significant inhibitory activities against other PTPs, including PTP1A, PTP2C, and PTP3A. In vivo studies have shown that DT-28-01 significantly reduces body weight gain in mice and improves insulin sensitivity. The mechanism of action for this effect is not known.
Odoratone was founded to develop novel small molecule inhibitors of protein tyrosine phosphatases (PTPs) for therapeutic use in cancer treatment. Our lead compound is DT-28-01 which is a highly potent, selective and irreversible inhibitor of the protein tyros
Chemical properties
Technical inquiry about: 3D-RAA96290 Odoratone
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