Tunicamycin V

CAS: 66054-36-2

Ref. 3D-RCA05436

Product Information

• Name: Tunicamycin V
• Brand: Biosynth
• Description: Tunicamycin V is an antibiotic and nucleoside analog, which is a secondary metabolite derived from various Streptomyces species. It functions predominantly by inhibiting the initial step of N-linked glycosylation, a critical post-translational modification process in eukaryotic cells. This inhibition occurs through the blockage of UDP-N-acetylglucosamine: dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase, thereby preventing the synthesis of dolichol-linked oligosaccharides and ultimately affecting protein folding and quality control mechanisms within the endoplasmic reticulum.

Chemical properties

• Molecular weight: 830.9 g/mol
• Formula: C₃₈H₆₂N₄O₁₆
• Purity: Min. 95%