2-Methyl-6-phenylpyridine-3-carboxylic acid
CAS: 66416-49-7
Ref. 3D-RCA41649
| 50mg | 193.00 € | ||
| 500mg | 724.00 € |
Product Information
- 2-Methyl-6-phenylnicotinic acid
- 3-Pyridinecarboxylic Acid, 2-Methyl-6-Phenyl-
2-Methyl-6-phenylpyridine-3-carboxylic acid is a compound that has been used as an antimicrobial agent. It is the most active of the aldehydes for the treatment of tuberculosis. 2-Methyl-6-phenylpyridine-3-carboxylic acid inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2 methyl 6 phenylpyridine 3 carboxylic acid also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g
Chemical properties
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