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Product Information
- Ethaden
- 2-[(6-Amino-9H-purin-8-yl)amino]ethan-1-ol
- Ethanol, 2-[(6-amino-9H-purin-8-yl)amino]-
- 2-[(6-Amino-9H-purin-8-yl)amino]ethanol
- Ethanol, 2-[(6-amino-1H-purin-8-yl)amino]-
2-[(6-Amino-1H-purin-8-yl)amino]ethan-1-ol (6APA) is a prodrug that is metabolized by the liver to 6-mercaptopurine (6MP). It is an antiinflammatory drug that has been shown to suppress collagen synthesis and inhibit the activity of proteases. 6APA is also used as a diagnostic agent for systemic diseases, such as reactive arthritis and systemic lupus erythematosus. This compound can be used in the treatment of inflammatory diseases, such as rheumatoid arthritis and Crohn's disease, due to its ability to inhibit the production of inflammatory compounds. The drug binds to affinity ligands which are associated with various proteins, including collagen. This binding prevents the formation of new proteins, which leads to cell death by inhibiting protein synthesis.
Chemical properties
Technical inquiry about: 3D-RCA81329 2-[(6-Amino-1H-purin-8-yl)amino]ethan-1-ol
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