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N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide
CAS:
Ref. 3D-RCC65241
10mg
863.00€
25mg
1,193.00€
Product Information
Name:N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide
Brand:Biosynth
Description:N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide (NHTB) is a histone deacetylase inhibitor that binds to the active site of the enzyme and inhibits its activity. It is selective for class I HDACs over class II HDACs. NHTB has been shown to inhibit acetylation of α-tubulin in vitro and in vivo. The compound also inhibits proliferation of T cells from patients with cutaneous T cell lymphoma and promotes apoptosis. NHTB also has antiangiogenic effects by inhibiting proliferation of endothelial cells.
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Chemical properties
Molecular weight:326.37 g/mol
Formula:C16H14N4O2S
Purity:Min. 95%
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