Product Information
- 1H,5H-benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-
- 9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid
- 9-fluoro-5,8-dimethyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
- 91618-36-9
- Ibaflin
- R 835
- S 25930
Ibafloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, which maintain the integrity of bacterial DNA. The terminal half-life of ibafloxacin is about 1.5 hours and the elimination half-life is about 5 hours. Ibafloxacin has been shown to be effective against multidrug-resistant bacteria such as methicillin resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii. Ibafloxacin has also been shown to be active against Gram negative bacteria such as Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis. Ibafloxacin has demonstrated a wide spectrum of activity in clinical studies, with an excellent response rate. This drug binds to microbial ribosomes by competitive inhibition and blocks the production of proteins vital for cell division. It has little
Chemical properties
Technical inquiry about: 3D-RDA61836 Ibafloxacin
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