![tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate](https://static.cymitquimica.com/products/3D/img/RFC05327.png "Click to enlarge")
tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate
CAS: 1391053-27-2
Ref. 3D-RFC05327
| 100mg | To inquire |
Product Information
tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1carboxylate (ABPC) is an agonist of the ion channel TRPV4. This compound has been shown to activate TRPV4 with a high affinity and selectivity. ABPC is a potent inhibitor of cell proliferation, which may be due to its ability to inhibit protein synthesis and DNA synthesis. ABPC has also been shown to inhibit the production of cytokines such as IL1β, IL6, and TNFα in lipopolysaccharide (LPS)-stimulated murine macrophages.
Chemical properties
Technical inquiry about: 3D-RFC05327 tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate
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