Product Information
- O-(2,4-Dimethoxy-benzyl)hydroxylamine hydrochloride
O-(2,4-Dimethoxybenzyl)hydroxylamine (DMBHA) is an inhibitor of histone deacetylases that is currently being researched for its potential use in cancer therapy. DMBHA has been shown to inhibit the production of phosphoramidate and phosphate derivatives, which are involved in cellular metabolism. This drug also has antitumor activity in vivo and inhibits the growth of cancer cells by blocking the enzymatic action of histone deacetylase enzymes. DMBHA binds to the active site of these enzymes and prevents the acetylation of lysine residues on histones, which results in a change in gene expression. DMBHA has also been shown to have efficacy against trypanosomiasis, as it inhibits protein synthesis and cell division.
Chemical properties
Technical inquiry about: 3D-RIA06766 O-(2,4-Dimethoxybenzyl)hydroxylamine
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