Product Information
Pep 2-8 is a cyclic peptide that induces autophagy, the process whereby cells destroy their own contents. Pep 2-8 has been shown to have beneficial effects on cardiac function and lowering low-density lipoprotein cholesterol (LDL-C). Pep 2-8 binds to the asialoglycoprotein receptor on the surface of liver cells, which allows it to be taken up by these cells. It also binds to a protein target in the cell membrane, which leads to increased uptake of Pep 2-8 by these cells. In addition, Pep 2-8 inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) and increases LDL receptors on the cell surface. This leads to an increase in hepatic uptake of LDL particles from the bloodstream and decreased cholesterol levels in blood plasma.
Chemical properties
Technical inquiry about: 3D-RLC01197 Pep 2-8
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