Product Information
Name:SMARt-420
Brand:Biosynth
Description:SMARt-420 is an experimental molecule that has been shown to have antimycobacterial activity against Mycobacterium tuberculosis. SMARt-420 is a non-natural chemical compound with a mycolic acid moiety, which can be synthesized from pentadecyl acetic acid. The synthesis of SMARt-420 has been achieved in a way that circumvents the biosynthetic pathway of mycolic acids and therefore does not require modification of the mycobacterial cell. SMARt-420 was found to have a high affinity for the M. tuberculosis cell membrane, inhibiting the growth and survival of this bacterium by affecting its lipid composition and membrane integrity. In addition, SMARt-420 inhibits cell wall biosynthesis by binding to the enzyme enoylpyruvyl transferase (Ept) in an irreversible fashion, blocking acetylation reactions that are essential for crosslinking of mycolic acids with glycer
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:340.34 g/mol
Formula:C17H19F3N2O2
Purity:Min. 95%
Technical inquiry about: SMARt-420
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