GSK1059865
CAS: 1191044-58-2
Ref. 3D-RXB04458
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Product Information
GSK1059865 is a clinical candidate for the treatment of Parkinson's disease. It is a selective and potent D2 receptor agonist that has been shown to be safe and well-tolerated in humans. GSK1059865 binds to the D2 dopamine receptor, which is located on neurons in the striatum, where it inhibits glutamate release. GSK1059865 also binds to other dopamine receptors, but with much lower affinity. This drug has been shown to increase locomotor activity in wild-type mice, as well as prevent locomotor deficits induced by the administration of 6-hydroxydopamine (6-OHDA).
Chemical properties
Technical inquiry about: 3D-RXB04458 GSK1059865
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