Product Information
- N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylc yclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]ami no]-2-pyridinecarboxamide
Mevociclib is a potent inhibitor of the Bcl-2 protein, which is considered to be a key regulator of cell death. It binds to the kinase domain of the Bcl-2 protein, inhibiting its function and promoting apoptosis. Mevociclib has shown potent antitumor activity in clinical studies against patients with high-risk diseases such as cancer and cell culture experiments against carcinoma cells. This drug also inhibits transcriptional regulation by suppressing specific genes that inhibit apoptosis pathways.
Chemical properties
Technical inquiry about: 3D-RXC98916 Mevociclib
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