Product Information
- 2,4,6-Trichlorobenzyl chloride
- Benzene, 1,3,5-trichloro-2-(chloromethyl)-
- Benzene, 1,3,5-trichloro-2-(chloromethyl)- (9CI)
- Benzene, 2-(chloromethyl)-1,3,5-trichloro-
- Brn 2503430
- Toluene, alpha,2,4,6-tetrachloro-
- Toluene, α,2,4,6-tetrachloro-
- alpha,2,4,6-Tetrachlorotoluene
- 1,3,5-Trichloro-2-(chloromethyl)benzene
- 4-05-00-00822 (Beilstein Handbook Reference)
- See more synonyms
1,3,5-Trichloro-2-(chloromethyl)benzene (TCMB) is a chemical compound that inhibits the synthesis of proteins and is used in cancer therapy. TCMB has been shown to inhibit protein synthesis by binding to the polymerase chain reaction enzyme transcriptase polymerase chain reaction. It also inhibits the activity of enzymes involved in lipid metabolism, such as lipases and cholesterol esterases. The serum bilirubin levels were found to be lower in mice treated with TCMB than in those not treated with TCMB. This may be due to the ability of this drug to inhibit the enzyme fatty acid synthase, which is responsible for synthesizing fatty acids. TCMB has been shown to induce apoptosis in bladder cells, which may be due to its inhibition of DNA synthesis and repair.
Chemical properties
Technical inquiry about: 3D-SAA29303 1,3,5-Trichloro-2-(chloromethyl)benzene
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