16β-Hydroxytestosterone
CAS: 17528-90-4
Ref. 3D-SAA52890
| 1mg | 331.00 € | ||
| 5mg | 857.00 € | ||
| 10mg | 1,291.00 € | ||
| 25mg | 2,420.00 € | ||
| 50mg | 3,872.00 € |
Product Information
- 4-androsten-16-beta 17-beta-diol-3-one
- Androst-4-En-3-One, 16,17-Dihydroxy-, (16Beta,17Beta)-
16β-Hydroxytestosterone is a synthetic androgen that is developed as a male contraceptive. The drug was reconstituted to be injected into the rat liver microsomes, which are the primary site of metabolism. 16β-Hydroxytestosterone inhibits the activities of NADPH-cytochrome P450 reductase (CPR) and cytochrome P450 enzymes, including CYP2D6, CYP3A4, CYP2C19, and CYP1A2. It also inhibits the activity of monoclonal antibodies that bind to CPR. In this study, 16β-hydroxytestosterone has been shown to inhibit the activity of p450 isozymes in Sprague-Dawley rats without affecting other enzyme activities. 16β-Hydroxytestosterone can be used for the treatment of prostate cancer or for contraception in males. This drug should not be used with nitrates or other drugs containing nitric oxide because
Chemical properties
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