Product Information
- 1-(1-Amino-1-methylethyl)-4-bromobenzene
- 2-(4-Bromophenyl)Propan-2-Amine
2-(4-Bromophenyl)propan-2-amine (BPAP) is an analogue of the antihistamine diphenhydramine. The BPAP analogues are selective for protein kinases, such as vegfr-2, cyclin, and cdk1. VEGFR-2 is a receptor tyrosine kinase that is activated by vascular endothelial growth factor and plays a role in angiogenesis. Cyclin is a serine/threonine protein kinase that regulates the cell cycle and CDK1 regulates the progression from G1 to S phase. In vivo efficacy studies have shown that BPAP inhibits these three kinases with an IC50 value of less than 1 μM in human tumor cells.
Chemical properties
Technical inquiry about: 3D-SAA79712 2-(4-Bromophenyl)propan-2-amine
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