PF-06747711

Ref. 3D-SAD57658

Product Information

• Name: PF-06747711
• Brand: Biosynth
• Description: PF-06747711 is a retinoid that binds to the retinoic acid receptor (RAR) and RAR-related orphan receptor (ROR) in the cell nucleus. These receptors are involved in the regulation of gene transcription, which controls the expression of proteins. PF-06747711 has been shown to be a potent inhibitor of inflammation and autoimmune diseases. It selectively binds with high affinity to RAR-α, RAR-γ, and RAR-β isoforms, as well as with low affinity to other retinoic acid receptor isoforms (RAR-β2 and RAR-δ). This drug also has proinflammatory effects on cytokine production.

Chemical properties

• Molecular weight: 497.51 g/mol
• Formula: C₂₆H₂₆F₃N₅O₂
• Purity: Min. 95%