Product Information
- Cycloheptanamine, N-methyl-
- Cycloheptylamine, N-methyl-
- N-Methylcycloheptylamine
- N-cycloheptyl-N-methylamine
- NSC 123851
N-Methylcycloheptanamine (NMCA) is a pyrimidine compound that has inhibitory activities against hexamethylenetetramine and aminopeptidase. NMCA also inhibits the immunosuppressive effect of cyclophosphamide, which is an anticancer drug. NMCA has been shown to be effective in treating autoimmune diseases and cancer. The inhibitory activity of NMCA on hexamethylenetetramine and aminopeptidase is due to its ability to react with these enzymes in nanomolar concentrations. Structural analysis has shown that NMCA binds to the enzyme by coordinating with the catalytic metal ions and the amino acid residues of the active site, forming a covalent bond with glutamic acid residue. This binding prevents substrate binding or product release, inhibiting enzyme activity.
Chemical properties
Technical inquiry about: 3D-SBA87065 N-Methylcycloheptanamine
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