Product Information
Name:2-Chloro-5-nitronicotinic acid
Brand:Biosynth
Description:2-Chloro-5-nitronicotinic acid is an inhibitor of HIV-1 reverse transcriptase. It binds reversibly to the active site of the enzyme and blocks its ability to synthesize DNA, thus inhibiting HIV replication. 2-Chloro-5-nitronicotinic acid also inhibits the activity of wild type and mutant forms of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with high potency. This drug has been shown to be effective against nevirapine resistant HIV strains. The molecular modeling studies suggest that 2-chloro-5 nitronicotinic acid binds to a hydrophobic pocket in the active site of HIV reverse transcriptase, which is different from other inhibitors such as AZT, ddI, and ddC.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:202.55 g/mol
Formula:C6H3ClN2O4
Purity:Min. 95%
Technical inquiry about: 2-Chloro-5-nitronicotinic acid
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