TBK1/IKKµ-IN-2
CAS: 1292310-49-6
Ref. 3D-SBC31049
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
TBK1/IKKµ-IN-2
Description:
BMS-345541 is a selective inhibitor of TBK1/IKKµ-IN-2, a protein complex that plays an important role in the inflammatory response. It inhibits the phosphorylation of IκBα and IKKβ (inhibitors of NF-κB), thereby suppressing the activation of NF-κB and its downstream inflammatory cytokines. BMS-345541 has been shown to inhibit proinflammatory cytokine production in vitro and in vivo in animals. The drug interacts with both catalytic subunits of TBK1/IKKµ-IN-2, suggesting that it may be used as a potential therapeutic agent for inflammatory conditions such as rheumatoid arthritis or Crohn's disease.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
457.52 g/mol
Formula:
C26H27N5O3
Purity:
Min. 95%
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HS code:
