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2-[4-(5-Bromofuran-2-amido)phenyl]acetic acid
CAS: 692290-41-8
Ref. 3D-SCB29041
| 1g | 998.00 € | ||
| 100mg | 253.00 € |
Product Information
2-[4-(5-Bromofuran-2-amido)phenyl]acetic acid is a potent blocker of voltage-gated sodium channels. It has been shown to inhibit the activation of these channels by increasing the threshold for depolarization and thereby producing a blockade of action potentials. This agent can be used as a research tool to study the role of voltage-gated sodium channels in cell biology, or as an inhibitor for therapeutic purposes. 2-[4-(5-Bromofuran-2-amido)phenyl]acetic acid binds to the ligand binding site at the extracellular end of voltage gated sodium channels and blocks their activity. The IC50 value is 0.1 μM and it has been shown to be selective for voltage gated sodium channels over other ion channel types such as potassium, calcium, and chloride channels.
Chemical properties
Technical inquiry about: 3D-SCB29041 2-[4-(5-Bromofuran-2-amido)phenyl]acetic acid
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