Product Information
- (2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid
- Antibiotic 81-484
- 2,10,12,16,18-Nonadecapentaenoic acid, 19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-
- PD 114721
Kazusamycin A is a β-amino acid that has potent antitumor activity. It inhibits the growth of subcutaneous tumors in mice, and has been shown to inhibit protein synthesis. Kazusamycin A also has potent inhibitory activity against fatty acid synthase, which is an enzyme that catalyzes the synthesis of fatty acids from acetyl-CoA. This inhibition may be responsible for its potent anti-tumor effects, as well as its ability to prevent tumor metastasis and cancer progression. Kazusamycin A also has been shown to have immunosuppressive effects and could be used for the treatment of autoimmune diseases such as rheumatoid arthritis or lupus erythematosus.
Chemical properties
Technical inquiry about: 3D-SDA09094 Kazusamycin A
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