Product Information
Tert-Butyl 3-aminobenzoate is an n-terminal synthetic pseudopeptide that has been shown to have potent inhibitory properties against proteases. This molecule is a transition state analogue and mimics the peptide bond in the active site of the protease enzyme, which leads to inhibition of the catalytic activity. Tert-Butyl 3-aminobenzoate has shown excellent inhibitory properties against a broad range of proteases and isosteres, with potency comparable to that of benzamidine and bestatin. This molecule also has hydrogen bonding interactions with an aspartic acid residue in the active site of the enzyme, which may be responsible for its inhibitory properties. Tert-Butyl 3-aminobenzoate is synthesized by reacting tert-butyl alcohol with 2-(3-hydroxyphenoxy)ethylamine in a two step process. The first step involves conversion to tert-butyl
Chemical properties
Technical inquiry about: 3D-SDA14682 tert-Butyl 3-aminobenzoate
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