Z-Glu-Tyr

CAS: 988-75-0

Ref. 3D-SEY-3018

Product Information

• Name: Z-Glu-Tyr
• Synonyms: Benzyloxycarbonyl-L-Glutamyl-L-Tyrosine, <span class="text-smallcaps">L</smallcap>-Tyrosine, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-α-glutamyl-, <span class="text-smallcaps">L</smallcap>-Tyrosine, N-[N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-α-glutamyl]-, Benzyloxycarbonyl-<span class="text-smallcaps">L</smallcap>-glutamyl-<smallcap>L</span>-tyrosine, N-Benzyloxycarbonyl-<span class="text-smallcaps">L</smallcap>-glutamyl-<smallcap>L</span>-tyrosine, N-Carbobenzoxy-<span class="text-smallcaps">L</smallcap>-glutamyl-<smallcap>L</span>-tyrosine, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-α-glutamyl-<smallcap>L</span>-tyrosine, NSC 89651, Tyrosine, N-(N-carboxy-<span class="text-smallcaps">L</smallcap>-α-glutamyl)-, N-benzyl ester, <smallcap>L</span>-, Z-Glu-Tyr-Oh
• CAS: 988-75-0

Description

Z-Glu-Tyr is a synthetic substrate of the enzyme cathepsin B. The amino acid sequence of Z-Glu-Tyr has been shown to be identical to the sequence of the natural substrate, L-glutaminyl-L-tyrosine. The activity of the enzyme cathepsin B can be inhibited by Z-Glu-Tyr due to its ability to form a covalent bond with cysteine residues in the active site. This inhibition prevents cleavage of peptide bonds and synthesis of polypeptides, which are necessary for cell growth and division. Z-Glu-Tyr is also an inhibitor of thiol proteases, such as papain and subtilisin, which are enzymes that hydrolyze peptide bonds in proteins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 444.43 g/mol
• Formula: C₂₂H₂₄N₂O₈
• Purity: Min. 95%