14-Epiandrographolide

CAS: 142037-79-4

Ref. 3D-SFA03779

Product Information

• Name: 14-Epiandrographolide
• Brand: Biosynth
• Description: 14-Epiandrographolide is a natural product that can be found in the plant Andrographis paniculata. It has been shown to have anti-inflammatory, anticancer, and antibacterial properties. 14-Epiandrographolide inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Chemical properties

• Molecular weight: 350.45 g/mol
• Formula: C₂₀H₃₀O₅
• Purity: Min. 95%