Product Information
- <span class="text-smallcaps">D</smallcap>-Alanine, N-[(hexahydro-1H-azepin-1-yl)carbonyl]-<smallcap>L</smallcap>-leucyl-1-methyl-<smallcap>D</span>-tryptophyl-3-(2-pyridinyl)-
- <span class="text-smallcaps">D</smallcap>-Alanine, N-[N-[N-[(hexahydro-1H-azepin-1-yl)carbonyl]-<smallcap>L</smallcap>-leucyl]-1-methyl-<smallcap>D</span>-tryptophyl]-3-(2-pyridinyl)-
- Fr 139317
- N-(azepan-1-ylcarbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-pyridin-2-yl-D-alanine
- N-[(Hexahydro-1H-azepin-1-yl)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-1-methyl-<smallcap>D</smallcap>-tryptophyl-3-(2-pyridinyl)-<smallcap>D</span>-alanine
- Pd 147953
FR 139317 is a selective endothelin receptor antagonist that binds to the endothelin-A receptor, inhibiting its activity. It has been shown to reduce myocardial infarct size and improve cardiac function in an animal model of myocardial infarct. FR 139317 also inhibits the growth of pulmonary artery smooth muscle cells in vitro and reduces endothelin-1 levels in a rat model of primary pulmonary hypertension. This drug also leads to an increase in natriuretic peptide levels and disease activity, as well as decreased blood pressure in rats with renal failure.
Chemical properties
Technical inquiry about: 3D-SFA37560 FR 139317
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
