Product Information
- 1-(6-{[(17Beta)-3-Methoxyestra-1,3,5(10)-Trien-17-Yl]Amino}Hexyl)Pyrrolidine-2,5-Dione
U-73343 is a selective inhibitor of the ubiquitin ligase activity of the p2y receptor. The in vitro method and whole-cell recordings have been used to show that U-73343 inhibits signal pathways involved in energy metabolism. It also inhibits intracellular Ca2+ levels and phospholipase production, which are related to receptor activity. This drug has been shown to be an experimental model for the study of cytosolic Ca2+. The p2y receptor is a G-protein coupled receptor that binds adenosine diphosphate (ADP) and plays a role in many physiological processes, including vasodilation, platelet aggregation, cell proliferation, and immune response. Inhibition of the ubiquitin ligase activity of this receptor may provide a new target for drug development.
Chemical properties
Technical inquiry about: 3D-SFA87812 U-73343
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