Abz-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Gln-EDDnp

CAS: 133407-82-6

Ref. 3D-SFQ-3916-PI

Product Information

• Name: Abz-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Gln-EDDnp
• Synonyms: <span class="text-smallcaps">L</smallcap>-Leucinamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl-N-(1-formyl-3-methylbutyl)-, (S)-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-, Calpain Inhibitor IV, Calpain inhibitor IV-2, Mg-132, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-<smallcap>L</span>-leucinamide, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, N-[(benzyloxy)carbonyl]leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]leucinamide, Z-Leu-Leu-Leu-aldehyde, N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide, L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-(1-formyl-3-methylbutyl)-, (S)-, L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-

Description

Abz-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Gln (EDDNP) is a novel and potent inhibitor of the polymerase chain reaction (PCR). It has been shown to inhibit the activity of DNA polymerases, which are key enzymes in DNA replication. EDDNP binds to the active site of the enzyme and blocks access to the DNA template. In addition, this compound inhibits mitochondrial membrane potential, as well as transcriptional regulation and detoxification enzymes. This compound has also been shown to be effective in vivo in mouse models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,486.66 g/mol
• Formula: C₆₁H₉₁N₂₁O₁₉S₂
• Purity: Min. 95%