Product Information
Name:HDAC8-IN-1
Synonyms:
- (2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
Brand:Biosynth
Description:HDAC8-IN-1 is a small molecule inhibitor of class I histone deacetylases (HDACs). It is a potent inhibitor of HDAC8, the most abundant HDAC in the human genome. In vitro studies have shown that HDAC8-IN-1 inhibits self-renewal and differentiation of cancer stem cells. In vivo, HDAC8-IN-1 treatment inhibited tumor growth in mouse models of leukemia and breast cancer. The pharmacological inhibition of HDAC8 with HDAC8-IN-1 has been shown to inhibit expression of genes involved in cell cycle regulation, angiogenesis, metastasis, and immune suppression.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:345.39 g/mol
Formula:C22H19NO3
Purity:Min. 95%
Technical inquiry about: HDAC8-IN-1
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