Z-Gly-Phe

CAS: 1170-76-9

Ref. 3D-SGF-3020

Product Information

• Name: Z-Gly-Phe
• Synonyms: Benzyloxycarbonyl-Glycyl-L-Phenylalanine, (2S)-2-[[2-(Benzyloxycarbonylamino)acetyl]amino]-3-phenyl-propanoic acid, (2S)-3-Phenyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid, (Carbobenzoxy)glycyl-<span class="text-smallcaps">L</span>-phenylalanine, (Carbobenzoxy)glycylphenylalanine, (Carbobenzyloxy)glycyl-<span class="text-smallcaps">L</span>-phenylalanine, <span class="text-smallcaps">L</span>-Alanine, N-(N-carboxyglycyl)-3-phenyl-, N-benzyl ester, <span class="text-smallcaps">L</span>-Phenylalanine, N-[(phenylmethoxy)carbonyl]glycyl-, <span class="text-smallcaps">L</span>-Phenylalanine, N-[N-[(phenylmethoxy)carbonyl]glycyl]-, Alanine, N-(N-carboxyglycyl)-3-phenyl-, N-benzyl ester, <span class="text-smallcaps">L</span>-, Carbobenzoxyglycylphenylalanine, L-Phenylalanine, N-(N-((phenylmethoxy)carbonyl)glycyl)-, N-(Benzyloxycarbonyl)glycyl-<span class="text-smallcaps">L</span>-phenylalanine, N-(Benzyloxycarbonyl)glycylphenylalanine, N-(Carbobenzoxy)glycyl-<span class="text-smallcaps">L</span>-phenylalanine, N-(Carbobenzyloxy)glycyl-<span class="text-smallcaps">L</span>-phenylalanine, N-(N-((Phenylmethoxy)carbonyl)glycyl)-L-phenylalanine, N-[(Phenylmethoxy)carbonyl]glycyl-<span class="text-smallcaps">L</span>-phenylalanine, N-[(benzyloxy)carbonyl]glycyl-L-phenylalanine, N-[(benzyloxy)carbonyl]glycylphenylalanine, Nsc 89642, Z-Gly-Phe-Oh

Description

Z-Gly-Phe is a peptide that inhibits protein synthesis by binding to the reactive site of a pancreatic enzyme. This site is normally occupied by a hydrogen bond and the compound binds to it by occupying this space, resulting in the inhibition of enzyme activity. Z-Gly-Phe has been shown to inhibit insulin-stimulated glucose uptake in rats, which may be due to its ability to bind with sodium carbonate. The binding constants of Z-Gly-Phe and its inhibitors have been determined using an analytical method that measures changes in pH. The optimum pH for Z-Gly-Phe is 8.5, which corresponds with the optimal pH for human pancreatic enzymes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 356.37 g/mol
• Formula: C₁₉H₂₀N₂O₅
• Purity: Min. 95%