Product Information
[1,3']Bipyrrolidinyl (BPY) is an antibacterial agent that binds to the receptor site on bacteria and inhibits bacterial growth. It has been shown to be effective against a number of Gram-negative bacteria including Haemophilus influenzae, Escherichia coli, and Pseudomonas aeruginosa. BPY has been found to hydrate at physiological pH and is eliminated from the body primarily in urine. BPY has also been found to have good plasma exposure due to its high lipid solubility. The affinity of BPY for bacterial ribosomes is greater than other antibacterial agents such as carboxylates or fluoroquinolones. The binding of BPY with bacterial ribosomes inhibits protein synthesis and cell division, leading to cell death by inhibiting the production of proteins vital for cell division.
Chemical properties
Technical inquiry about: 3D-SKA24199 [1,3']Bipyrrolidinyl
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