Methyl 4-hydroxy-2-sulfanylquinoline-3-carboxylate

CAS: 892294-34-7

Ref. 3D-SKB29434

Product Information

• Name: Methyl 4-hydroxy-2-sulfanylquinoline-3-carboxylate
• Brand: Biosynth
• Description: Methyl 4-hydroxy-2-sulfanylquinoline-3-carboxylate (MSQ) is a synthetic molecule that has shown to have antiviral activity against the hepatitis B virus. This compound is a competitive inhibitor of the virus and prevents it from infecting cells. MSQ has also been shown to inhibit other viruses, such as herpes simplex virus, influenza A and C, rotavirus, and human immunodeficiency virus type 1 (HIV-1). The high inhibition of MSQ can be attributed to its ability to form hydrogen bonds with the amino acid residues in viral proteins. Additionally, MSQ interacts with anions in the active site of the enzymes that are necessary for viral replication through alkylation reactions.MSQ has been found to be selective for influenza A and C by binding at different sites on the enzyme compared to other compounds like zanamivir and oseltamivir. The single-crystal x

Chemical properties

• Molecular weight: 235.26 g/mol
• Formula: C₁₁H₉NO₃S
• Purity: Min. 95%