Leu-pNA

CAS: 4178-93-2

Ref. 3D-SLN-3014

Product Information

• Name: Leu-pNA
• Synonyms: L-Leucine p-Nitroanilide, (2S)-2-Amino-4-methyl-N-(4-nitrophenyl)pentanamide, (2S)-4-methyl-1-[(4-nitrophenyl)amino]-1-oxopentan-2-aminium, <span class="text-smallcaps">L</span>-Leucine p-nitroanilide, <span class="text-smallcaps">L</span>-Leucyl-4-nitroanilide, <span class="text-smallcaps">L</span>-Leucyl-p-nitroanilide, H-Leu-Pna, L-Leucine-p-nitroanilide, Leucine p-nitroanilide, N-(4-nitrophenyl)-L-leucinamide, N-<span class="text-smallcaps">L</span>-Leucyl-p-nitroanilide, N-α-<span class="text-smallcaps">L</span>-Leucine p-nitroanilide, Pentanamide, 2-amino-4-methyl-N-(4-nitrophenyl)-, (2S)-, Pentanamide, 2-amino-4-methyl-N-(4-nitrophenyl)-, (S)-, Valeranilide, 2-amino-4-methyl-4′-nitro-, <span class="text-smallcaps">L</span>-

Description

Leu-pNA is a protein synthesis inhibitor that binds to the active site of the enzyme peptidyl prolyl cis-trans isomerase (PPIase). This inhibitor prevents the enzyme from catalyzing the conversion of proline residues in peptides to their cis or trans isomers. Leu-pNA has been shown to inhibit proteolytic enzymes such as soybean trypsin and activated proteases, and also has an inhibitory effect on polymerase chain reaction (PCR) enzyme activities. The binding of Leu-pNA to PPIase can be reversed by heating at 60°C for 20 minutes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 251.28 g/mol
• Formula: C₁₂H₁₇N₃O₃
• Purity: Min. 95%