MOCAc-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2

Ref. 3D-SMO-3212-V

Product Information

• Name: MOCAc-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2
• Synonyms: 7-Methoxycoumarin-4-yl) acetyl-L-Seryl-L-Glutamyl-L-Valyl-L-Asparaginyl-LLeucyl-L-Aspartyl-L-Alanyl-L-Glutamyl-L-Phenylalanyl-L-Argi nyl-[N?-(2,4-Dinitrophenyl)-L-Lysyl]-L-Arginyl-L-Arginine Amide
• Brand: Biosynth
• Description: MOCA is a small peptide with anti-inflammatory properties that binds to the receptor IL-1R. It has been shown to inhibit sodium currents in neurons by binding to the Na+ channel and preventing the influx of sodium ions, which leads to an inhibition of action potentials. MOCA has also been shown to bind with high affinity to the IL-1R and blocks its activity. This inhibition of IL-1R leads to decreased production of proinflammatory cytokines.MOCA has not been shown to have any affinity for other receptors or ligands.

Chemical properties

• Molecular weight: 2,001.1 g/mol
• Formula: C₈₆H₁₂₅N₂₇O₂₉
• Purity: Min. 95%