(3S,4S)-Tofacitinib

CAS: 1092578-47-6

Ref. 3D-STB57847

Product Information

• Name: (3S,4S)-Tofacitinib
• Brand: Biosynth
• Description: (3S,4S)-Tofacitinib is a tyrosine kinase inhibitor that is used to treat cancer and autoimmune diseases. This drug binds to the enzyme deoxycytidine kinase, which is an important enzyme in DNA synthesis. Tofacitinib citrate is a prodrug that is converted into the active form of the drug in vivo by esterases. (3S,4S)-Tofacitinib has been shown to induce pluripotent stem cells from human bone marrow and has demonstrated efficacy in treating alopecia areata in animal models. The safety profile of this compound appears to be similar to that of other oral tyrosine kinase inhibitors, with side-effects such as diarrhea, nausea, and fatigue being most common. (3S,4S)-Tofacitinib citrate has also been found to be effective in reducing prostate hyperplasia when administered orally at dosages between 10

Chemical properties

• Molecular weight: 312.37 g/mol
• Formula: C₁₆H₂₀N₆O
• Purity: Min. 95%