dNaM

CAS: 1117893-19-2

Ref. 3D-SUB89319

Product Information

• Name: dNaM
• Brand: Biosynth
• Description: dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.

Chemical properties

• Molecular weight: 274.31 g/mol
• Formula: C₁₆H₁₈O₄
• Purity: Min. 95%