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2-(Difluoromethoxy)-5-nitropyridine
CAS: 1192813-41-4
Ref. 3D-SXB81341
1g | To inquire | ||
5g | To inquire | ||
10g | To inquire | ||
25g | To inquire | ||
500mg | To inquire |
Product Information
2-(Difluoromethoxy)-5-nitropyridine is a reagent that is used in organic synthesis. This compound is synthesized by the reaction of 2-fluoro-5-nitrobenzaldehyde with difluoromethylmagnesium bromide. The yields for this compound are high and it can be used as a starting material for various chemical reactions, such as formylations, nucleophilic aromatic substitutions, or sulfonylations. The synthesis of 2-(difluoromethoxy)-5-nitropyridine involves an electrophilic substitution at the C2 position of the pyridine ring with the trifluoromethyl group to produce a fluorine atom. The mechanism of this reaction is catalysed by strong bases, such as potassium fluoride.
Chemical properties
Technical inquiry about: 3D-SXB81341 2-(Difluoromethoxy)-5-nitropyridine
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