Product Information
- (2S)-2-[5-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 2-(5-((2E)-3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)-
- 4H-1-Benzopyran-4-one, 2-[5-(3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-, [S-(E)]-
- 4H-1-Benzopyran-4-one, 2-[5-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-, (2S)-
Kuwanon E is a cox-2 inhibitory that inhibits the production of tumor necrosis factor-α (TNF-α). Kuwanon E is extracted from the bark of the neocyclomorusin tree, which grows in Cameroon. The extract contains prenylflavones, nonsteroidal anti-inflammatory drugs, and a variety of other chemical compounds. It also has hypoglycemic effects and can be used to treat oral pathogens. Kuwanon E blocks the initiation of apoptosis by inhibiting fatty acid synthase and inhibiting TNF-α signaling pathways. This agent also has an anti-inflammatory effect on THP-1 cells by preventing oxidative stress and activation of NFκB.
Chemical properties
Technical inquiry about: 3D-TCA40105 Kuwanon E
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