Product Information
- 4-Hydrazinoquinoline hydrochloride (1:1)
- Quinoline, 4-Hydrazinyl-, Hydrochloride (1:1)
4-Hydrazinoquinoline hydrochloride is a cation with a molecular weight of 176.2. It is cytotoxic and inhibits cancer cell growth. 4-Hydrazinoquinoline hydrochloride has been shown to be effective against lymphoid, breast, colon, and prostate cancer cells in vitro with IC50 values of 0.5 to 2 μM. This drug has been shown to bind to DNA by forming a Schiff base with the amine group of guanine residues in the DNA backbone. This binding leads to changes in DNA conformation that inhibit transcription and replication as well as protein synthesis and cell division.
Chemical properties
Technical inquiry about: 3D-TCA50041 4-Hydrazinoquinoline hydrochloride
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