Product Information
- (1,1'-Biphenyl)-2-ol, 4'-methoxy-3',5-di-2-propenyl-
- 3,5′-Diallyl-2′-hydroxy-4-methoxybiphenyl
- 4-Methoxyhonokiol
- 4-O-Methyl honokiol
- 4′-Methoxy-3′,5-di-2-propen-1-yl[1,1′-biphenyl]-2-ol
- 4′-O-Methylhonokiol
- NSC 293101
- [1,1'-Biphenyl]-2-Ol, 4'-Methoxy-3',5-Di-2-Propen-1-Yl-
- [1,1′-Biphenyl]-2-ol, 4′-methoxy-3′,5-di-2-propen-1-yl-
- [1,1′-Biphenyl]-2-ol, 4′-methoxy-3′,5-di-2-propenyl-
- See more synonyms
4-O-methyl honokiol is a natural compound that has been shown to have anti-inflammatory and antitumor activities. It inhibits the growth of squamous cell carcinoma, human polymorphonuclear leukocytes, and chronic cough in mice. 4-O-Methyl honokiol also inhibits the activity of protein kinase C (PKC) and phosphatidylinositol 3-kinase (PI3K), which are key enzymes in the apoptosis pathway. This compound binds to DNA and alters its structure, making it unable to bind to transcription factors necessary for gene expression. 4-O-Methyl honokiol also decreases the rate constant for p-glycoprotein substrate transport in mitochondria, leading to a decrease in mitochondrial membrane potential.
Chemical properties
Technical inquiry about: 3D-TCA59215 4-o-Methyl honokiol
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