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2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
CAS: 1343040-07-2
Ref. 3D-TDC04007
| 50mg | 262.00 € | ||
| 500mg | 1,041.00 € |
Product Information
The synthesis of 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid is accomplished through an asymmetric, stereoselective, catalytic route. The first step in the synthesis is conversion of glycine to the corresponding N-protected glycine methyl ester by reaction with benzyl chloroformate followed by protection of both carboxylic acid groups as FMOC derivatives. The key steps are a diastereoselective hydrogenation of the cyclopentane ring system and an efficient alkylation reaction of the resulting alcohol with 9H-fluoren-9-ol.
2-[Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid has been shown to be a potent inhibitor against bacterial growth. It binds to bacterial topoisomerase IV enzyme, which
Chemical properties
Technical inquiry about: 3D-TDC04007 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
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