Pyrindamycin A

CAS: 118292-36-7

Ref. 3D-TEA29236

Product Information

• Name: Pyrindamycin A
• Synonyms: (+)-Duocarmycin C₂, Antibiotic SF 2582A, Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R,8S)-, Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R-trans)-, Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate, Pyrindamycin, Sf 2582A, methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate, pyrindamycin A

Description

Pyrindamycin A is a natural product that is the product of a fermentation process. It has been shown to have cytotoxic properties and can be used as a chemotherapeutic agent for leukemia and other cancers. Pyrindamycin A is also an antibacterial, with activity against gram-positive and gram-negative bacteria. The mechanism of action involves steric interactions with the target tissue, leading to morphological changes in the bacterial cell wall by inhibiting the synthesis of peptidoglycan. Pyrindamycin A has been shown to inhibit leukemia inhibitory factor (LIF) production in mouse bone marrow cells, which may be due to its ability to bind to DNA. This molecule also has biological properties that are similar to those of monoclonal antibodies, including binding and inhibition of protein synthesis in sensitive cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 544 g/mol
• Formula: C₂₆H₂₆ClN₃O₈
• Purity: Min. 95%